The U.S. Environmental Protection Agency has set a maximum contaminant level of 2 ppb of vinyl chloride for public drinking water supplies. Angiosarcoma attacks the lining of blood vessels, and can occur in any area of the body. It burns easily. Vinyl chloride exposure has been shown to increase the risk of a rare form of liver cancer called angiosarcoma. Primary exposure to vinyl chloride occurs through inhalation. Under the authority of the Federal Advisory Committee Act (FACA) P.L. September 2015 Vinyl Chloride What is vinyl chloride? Exposure Sources of Vinyl Chloride. One reason why PVC is so toxic is that it is often mixed with softening chemicals called plasticizers, the most well known variety being phalates. Sloane K. Tilley, Rebecca C. Fry, in Systems Biology in Toxicology and Environmental Health, 2015. Vinyl chloride is a synthetic, colorless gas. (1,2) Acute Exposure Guideline Levels. PREFACE. Most vinyl chloride is used to make polyvinyl chloride (PVC) plastic and vinyl products. Vinyl Chloride 75-01-4 _____ Hazard Summary . Studies in workers who inhale vinyl chloride over many years show an increased risk of … Vinyl Chloride 1. References: cancer.gov, OSHA, IARC, CDC Portal hypertension, liver fibrosis, and angiosarcoma of the liver (ASL) have been reported among workers exposed to vinyl chloride monomer (VCM) since the 1970s. Acute (short-term) exposure to high levels of vinyl chloride in air has resulted in central nervous system (CNS) effects, such as … It is not stable at high temperatures. The odds ratio (OR) for ever exposure to vinyl chloride was 1.05 (95% confidence interval, CI: 0.68-1.62) and a modest, non-significant increase in the risk of lung cancer was found in the highest exposed subgroup. Do standards exist for exposure to vinyl chloride? A statement of each employee's suitability for continued exposure to vinyl chloride including use of protective equipment and respirators, shall be obtained from the examining physician promptly after any examination. Polyvinyl chloride, also known as PVC or vinyl, is arguably one of the most toxic types of plastic in our lives. This fact sheet discusses possible health risks from exposure to low levels of vinyl chloride typically found in drinking water wells. 5. Occupational exposure to vinyl chloride may occur in those workers concerned with the production, use, transport, storage, and disposal of the chemical. Vinyl chloride is classified as Group 1 carcinogen by the IARC, meaning it is seen as a definite cause of cancer in humans. (1,2) Assessing Personal Exposure Vinyl chloride can be detected in urine and body tissues, but the tests are not reliable indicators of total exposure. 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